In December , the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. Currently, many people obtain CBD. The health benefits of CBD oil are being studied by world-class researchers around the world. We analyzed and summarized 17 of the best. Preclinical and clinical studies show CBD possesses a wide range of therapeutic properties, including antipsychotic, analgesic, neuroprotective, anticonvulsant.
It's marketed as a compound that can help relieve anxiety — and, perhaps, help ease aches and pains, too. Part of the appeal, at least for people who don't want to get high, is that CBD doesn't have the same mind-altering effects as marijuana, since it does not contain THC, the psychoactive component of the plant. Another rationale Ferry's heard from clients about their CBD use: But with this popularity the hype may have gotten ahead of the science.
CBD oil, often dispensed under the tongue with a dropper, has been regulated as a supplement in the U. So strength and purity may vary from brand to brand, or even bottle to bottle, scientists say. Researchers now are trying to nail down CBD's effects. Esther Blessing , a psychiatrist and researcher at New York University. So far, evidence of the substance's anti-anxiety effect comes from animal research and from very small, short-term human studies that suggest CBD exhibits anti-inflammatory and anti-anxiety properties.
These preliminary findings piqued Blessing's interest. For instance, she points to a study of a few dozen people, some of whom had social anxiety disorder, who were asked to speak in front of a large audience. Researchers compared anxiety levels in people after they took CBD, compared to those who got the placebo or nothing at all. The participants didn't know if they'd been given the drug or the placebo. Last week, a panel of FDA advisers recommended approval of the drug to treat severe seizure disorders in children.
And what did the scientists find? Now, with funding from the National Institutes of Health, Blessing and group of collaborators are about to begin a clinical trial to test whether CBD can help people with post-traumatic stress disorder who also have moderate or severe alcohol use disorder. During the study, 50 participants with PTSD coexisting with alcohol use disorder will be given either milligrams of CBD daily, or a placebo. The participants will be given a pharmaceutical-grade CBD, which is more reliable in strength and purity than the supplements that are currently available for sale to the public.
Another Phase 2 clinical trial to test efficacy and side effects is exploring whether CBD might help prevent relapse in opioid abusers by reducing craving for the drug. Hurd has been trying to rally other top scientists to study CBD's effects and potential benefits in the treatment of substance abuse. It may seem counterintuitive that a component of marijuana could be useful in treating addiction to another drug.
But Blessing says using CBD is very different from using marijuana. Research has shown that CBD can be an effective anti-inflammatory agent, reduce anxiety, reduce motor symptoms tremor, rigidity, bradykinesia and maintain circadian sleep rhythms.
The earliest symptoms are often subtle problems with mood or mental abilities. A general lack of coordination and an unsteady gait often follow. The most commonly reported potential side effects of CBD usage were diarrhea and bloating, with some also reporting nausea. Specifically, in dementia, some patients reported increased tremor with high dose CBD. As with any new treatment, patients and caregivers should monitor effects and outcomes closely. This does not mean it is non-psychoactive, but rather that the psychoactive effects are often beneficial and non-intoxicating vs.
THC has also shown medicinal benefits for patients, particularly those suffering from pain or inflammation, especially when combined with CBD for consumption by patients. CBD usually makes humans feel more awake and alert without negative impact on sleeping patterns.
What is more likely happening is that cannabis strains being used by a patient that have high levels of CBD also contain a potentially sedating terpene such as myrcene. Medical, locally sourced cannabis has consistently produced the best CBD source as it is held to stricter laboratory testing for potency and contaminants. Hemp based CBD would not technically have this restriction, but the sourcing and labeling risks are many. Medical based CBD has been legalized in more than 30 states and recreationally legal in a growing number of US locations.
CBD comes in many forms, it can be inhaled, taken in pill format as an oil to name just a few options. Most CBD patients prefer non-inhalable options, such as CBD-rich cannabis oil products that can be consumed orally such as gel caps , squeezed under the tongue with liquid dropper or as delivered via patches on the skin like band aids.
The effects of orally administered CBD can last for up to 4 hours, and the onset of effects has shown to take between minutes. In cases of acute symptoms that require immediate attention, inhalation of concentrated CBD rich cannabis effects can be felt within minutes and last up to 1 or 2 hours.
Both forms are widely available at medical marijuana dispensaries. Despite CBD being sold in health food stores, tobacco shops, on Amazon, etc. Legally recognized state ID is required for purchase. In spite of the diverse legal status in different states, CBD can be purchased online and delivered legally to all 50 states.
The most common means to obtain CBD rich medical marijuana is from a state licensed dispensary. These dispensaries can be found by searching on any number of dispensary directories Leafly, Yelp, etc. For those that have trouble with transportation, another increasingly available option would include delivery-based options. However, while convenient for senior patients, these options are not available in every city or town.
Finally, CBD can be purchased over the Internet and delivered to all 50 states. One reputable seller is CBD Pure. One can visit their website here. Given the lack of regulation in the CBD marketplace and given the challenges of self-reporting of the benefits with persons with dementia, getting the CBD dosage correct is especially challenging.
Even though no prescription is required to purchase CBD, many doctors are still knowledgeable about the product and can provide dosage recommendations.
NIH Research on Marijuana and Cannabinoids
ARTICLE TYPES; Books and documents; Clinical trials; Meta-analysis; Randomized controlled trials; Review articles; Systematic reviews. TEXT AVAILABILITY. The body of research on cannabidiol, CBD oil benefits, THC, and other cannabinoids has grown exponentially in the past decade. The following brings together. Cannabis has been used medicinally for millennia, but has not been approved by the U.S. Food and Drug Administration to treat any medical.